The loss of the Seven-Hour War is still fresh. In the shadow of a rising Combine fortress known as the Citadel, residents of City 17 learn to live under the rule of their invaders. But among this scattered population are two of Earth's most resourceful scientists: Dr. Eli Vance and his daughter Alyx, the founders of a fledgling resistance. You and your father were relocated to City In the years since, you've continued your clandestine scientific activity—performing critical research, and building invaluable tools for the few humans brave enough to defy the Combine.

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The games combine shooting combat, puzzles, and storytelling. The original Half-Life , Valve's first product, was released in for Windows to critical and commercial success. Players control Gordon Freeman , a scientist who must survive an alien invasion. The innovative scripted sequences were influential on the FPS genre, and the game inspired numerous community-developed mods , including the multiplayer games Counter-Strike and Day of Defeat. In , Valve released Half-Life 2 to further success, with a new setting and characters and physics-based gameplay. The first game in the Portal series , set in the same universe as Half-Life , was released in In , after years of speculation, Valve released its flagship virtual reality game, Half-Life: Alyx. Half-Life was Valve's first product, released on November 19, for Windows.
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NCBI Bookshelf. Jericho Hallare ; Valerie Gerriets. Authors Jericho Hallare 1 ; Valerie Gerriets 2. Half-life in the context of medical science typically refers to the elimination half-life. This article will focus on first-order half-life elimination as it is the most frequently encountered in clinical practice. Total drug exposure over time is represented in these graphs as the integral area under the curve AUC. After solving the differential equation, one can obtain the half-life equation that is commonly tested on and used in clinical practice Equation 2. From this equation, one can quickly determine the half-life of a drug, given its predetermined rate constant k. An alternative half-life equation exists that relates half-life to other pharmacokinetic parameters known as the volume of distribution and clearance Equation 3.
Half-Life is a first-person shooter video game developed by Valve and published by Sierra Studios for Microsoft Windows in It was Valve's debut product and the first game in the Half-Life series. Players assume the role of Gordon Freeman , a scientist who must escape the Black Mesa Research Facility after it is invaded by aliens. The core gameplay consists of fighting alien and human enemies with a variety of weapons and solving puzzles. Unlike many other games at the time, the player has almost uninterrupted control of Freeman, and the story is told mostly through scripted sequences seen through his eyes.